New Gas Chromatography Products for 2019–2020

Among Armstrong's many accomplishments is the development of ionic liquid stationary phases for capillary GC. [...]the American Chemical Society Division of Analytical Chemistry Satinder Ahuja New Investigator Award in Separation Science was presented to. Table III provides a listing of accessories and consumables launched over the past year. Besides several short courses associated with Pittcon, additional training and educational resources are available for 2020.

Evaluating Take 5: Virtual Learning Sessions on Trauma Informed Care for Healthcare Staff During COVID-19

In 2018, CAI, an organization that provides national level training and capacity-building developed a TIC implementation model, now delivered in HIV and primary care agencies throughout the United States to integrate TIC into their culture, environment, and service delivery. In 2018, an organization that provides national level training and capacity-building, Cicatelli Associates, Inc. (CAI), developed a TIC implementation model, now delivered in HIV and primary care agencies throughout the United States to integrate TIC into their culture, environment, and service delivery. PWH who have experienced trauma are 58% less likely to adhere to their antiretroviral treatment compared to PHW who have not experienced trauma (Brown. Since 2018, CAI, a national training and technical assistance organization, has developed and implemented a TIC implementation model to build the capacity of primary care agencies and their healthcare staff to integrate TIC throughout their cultures, environments, and service delivery. The motivation for this model is based on the understanding that primary care providers play a critical role in identifying and addressing past trauma with clients, as opposed to simply relying on referrals to external mental health services to support these needs. CAI technical assistance providers offer capacity building and training to staff at these agencies to implement components of the model to ensure successful integration of TIC into agency culture, environment, and service delivery.

WHAT WE WISH WE KNEW BEFORE GOING ONLINE: Lessons Learned From Implementing an Online MBA

Montclair State University (MSU) is New Jerseys second-largest public institution. As online education continues its rapid-paced growth, MBA programs have been some of the most common online degrees. In 2016, Montclairs Feliciano School of Business entered this crowded online MBA market. After a false start and sometimes rocky development, the online MBA was successfully launched in the fall of 2016. The program grew so fast that the leadership team needed to find innovative ways to handle the number of students. The lessons learned by the online MBA leadership team are detailed below.

Increasing Access to a Diverse Mental Health Workforce through Emergency Reciprocity Licensure

New Jersey's COVID-19 Temporary Emergency Reciprocity Licensure Program provided temporary licenses to more than 31000 out-of-state healthcare practitioners, over a quarter of whom were mental health providers. As the need for mental health care accelerated during the pandemic, especially among health disparity populations, expanding mental health provider pools may be a critical tool to increase access to care. In January 2021, we surveyed New Jersey's temporary licensees. We analyzed over 4500 mental health provider responses to examine the impact of the temporary licensure program on access to mental health care overall and on enhancing a diverse mental health workforce. Over 3700 respondents used their temporary license to provide mental health care to New Jersey patients. About 7% of respondents self-identified as Hispanic, 12% Black, 6% Asian, 1% American Indian or Alaska Native, and 0% (more than 5) Native Hawaiian or other Pacific Islander. They treated about 30100 New Jersey patients, 40% of whom were new to the provider, and 81% delivered care exclusively using telehealth. Respondents conversed with patients in at least 13 languages. About 53% served at least one patient from an underserved racial/ethnic minority group. Our findings suggest that temporary out-of-state mental health providers helped enhance mental health care continuity and access. Copyright 2023 Federation of State Medical Boards. All Rights Reserved.

Mental Health Issues for Frontline Hospital Staff During Height of Covid Pandemic 2020

IntroductionWhen the SARS-Cov2 virus hit the New York and New Jersey metropolitan area in Spring 2020, hospitals and hospital workers were hit hard with a new unknown pathogen that either killed people or made them very ill. There were large numbers of severely ill patients that strained resources. Hospital workers had extraordinary stress with multiple additional patients, the need to use personal protective equipment (PPE) in short supply, and faced with a pathogen that had no treatments beyond care and support initially.MethodsWe surveyed our hospital workers in late Spring 2020 to identify the main stressors and find out what measures were helpful. An online anonymous survey included questionnaires about sleep, mood, outside stressors, helpful measures, and how they coped generally. All levels of hospital workers were surveyed. Resources were provided to all respondents.ResultsOver 240 individuals responded to the survey;most respondents were women (76%). ‘Workplace stressors' topped the chart for 98 of our respondents. The worst workplace stressor that was cited was ‘irritable workforce,' but ‘lack of ‘protocols' and ‘shortage of PPE' were also cited as stressors. ‘Other' (not described) and ‘taking care of an ill relative' were rated highly. Those who had ‘symptoms everyday:' Anhedonia (loss of pleasure or interest), 13%;feeling down and hopeless, 12%;sleep disturbance, 41%;low energy, feeling tired, 29%;appetite disturbance, 26%;poor concentration and attention, 15%. Respondents told us what resources they used and what was most helpful;exercise was most frequently cited as helpful.Lessons Learned and DiscussionVarious resources for formal and informal mental health support were provided to all respondents at the time of survey. Our hospital mounted its own response with support services, as did our medical school and university. A "warm line" was available through the Department of Psychiatry from late March 2020;tip sheets and online groups were widely circulated;State Department of Health provided resources. There were formal peer support sessions and workers helped each other. Medical students provided child care, shopping, and transport. We learned that extra support for workers and more frequent rest and recharge time are important. A weekly "town hall" was instituted and a weekly update about the hospital and support in healthy activities are widely circulated to employees. Those with active PTSD (some were very disturbed by the number of deceased patients) were referred to professional providers. Hospitals need to be ready to deal with epidemics and pandemics more effectively in order to mitigate stress and support workers. Being prepared, not just with equipment, but with protocols in how to proceed should another pandemic come. We learned that listening to workers is important. Workers also need to know how valued they are.FundingDepartment of Psychiatry, New Jersey Medical School

Championing Nursing Workforce Through Innovative Dialogues and Collaborations

Cumulatively, it has had a hand in the great resignation, pushed hospitals profit margins into the nether regions, and reached into the ranks of nursing students, as well as their faculty, the academic workforce (Leaver et al., 2022). [...]the public, while grateful at least in the most difficult days of the pandemic, not only failed to translate these actions into strong policies that would result in much tangible change on a national level (Aiken et al., 2022), they have seemingly turned their own frustrations with health care delivery upon their former heroes, nurses themselves, resulting in episodes of nurse-directed assaults and violence, with an average of two nurses assaulted each hour in the United States (Press Ganey, 2022). According to Becker's Hospital Review (2022), an industry news source, "hospital margins are collapsing, and some organizations wonder if it's even possible to make money in the acute care space." Left unabated, shortages will result in patients receiving less face time with health care workers, lengthening current delays in diagnosis, reducing quality of care, burdening the health system (and patients) with our medical errors, and regretfully, increasing disparities and failure to adequately address social determinants of health.

COVID in the nursing homes: the US experience

The death toll in nursing homes accounted for almost 30 per cent of total Covid-19 deaths in the US during 2020. We examine the course of the pandemic in nursing homes focusing especially on whether nursing homes could have been better shielded. Across all nursing homes the key predictor of infections and deaths was community spread, i.e. a factor outside of the control of nursing homes. We find that higher-quality nursing homes, as measured by the CMS Five-Star Rating system, were not better able to protect their residents. Policy failures from the CDC and FDA, especially in the early stages of the pandemic, created extended waiting times for Covid-19 tests and slowed attempts to isolate infectious residents. But once infections were widespread, testing would have had to have been much greater to have had an appreciable effect on nursing home deaths. We find, however, that starting vaccinations just 5 weeks earlier could have saved in the order of 14,000 lives and starting them ten weeks earlier could have saved 40,000 lives.

Comparison of STEMI Door-To-Device Time During the COVID-19 Crisis in a New Jersey Inner City Community Hospital.

As the novel COVID-19 pandemic was on the rise, its impact on the healthcare system was devastating. Patients became more reluctant to present to the hospital and elective procedures were being postponed for patient safety. We wanted to assess the effects of the COVID-19 pandemic on the door-to-device time in our small community hospital in the heart of Trenton, New Jersey. We created a retrospective study that evaluated all STEMI cases that presented to our institute from January 2018 until the end of May, 2021. Our primary outcome was the door-to-device time. Secondary outcomes were the length of hospital stay, ICU admission, length of ICU stay, cardiac arrest, and death during the hospitalization. We studied 114 patients that presented with STEMI to our emergency department, 77 of these patients presented pre-COVID-19, and 37 presented during the pandemic. Our median door-to-device for STEMI cases pre-COVID-19, and during the pandemic were 70 min (IQR 84-57) and 70 min (IQR 88-59) respectively with no significant difference found (P-value 0.55, Mann Whitney Test). It is, however, interesting to note that the number of STEMI admissions significantly decreased during the pandemic era. There are limitations to our study, most noticeably the number of STEMI cases at our small community hospital which limits its generalizability. Moreover, we did not assess other comorbidities which might have confounded our outcomes and we were also unable to follow patients post-discharge to assess the long-term sequela of their STEMI admission. Therefore, more dedicated studies of this clinical conundrum are required to further assess and implement guidelines for the future.

COVID-19 Vaccine Hesitancy among New Jersey Teachers and Impacts of Vaccination Information Dissemination.

Vaccine hesitancy continues to be prevalent in the United States, especially in relation to the COVID-19 vaccines and its boosters, which have been made increasingly available for public use as the pandemic has progressed. There continues to be concern surrounding the safety and health of secondary or high school education professionals as they transition back to in-person learning and working opportunities. The present study highlights how information dissemination regarding the COVID-19 vaccine has varied among New Jersey secondary or high school teachers throughout the pandemic. The survey was completed online through the PsychData platform by 269 participants between March and July 2022. Participants received the opportunity to complete the survey via email. Afterwards, data were exported and analyzed using Microsoft Excel and SAS 9.4 Analytics Software and stratified by various clinical and demographic-based variables. While trusted agencies and media outlets identified by participants varied, most participants identified the Centers for Disease Control and Prevention (65.4%), primary care providers (37.5%), and state health departments (28.6%) as their top trusted sources for information related to COVID-19 vaccines. Overall, COVID-19 vaccination advocacy and educational efforts should continue across the state of New Jersey and elsewhere, especially as more variants emerge and boosters become available.

Signature Pedagogies versus Trauma Informed Approaches: Thematic Analysis of Graduate Students' Reflections

The COVID-19 pandemic is evidenced as a traumatic event, impacting college students preparing for healthcare careers. Trauma-informed pedagogical evidence-based recommendations include clear instruction, faculty availability, and open acknowledgment of challenges. This study explored trauma-informed mechanisms embedded in a fully online health sciences course at a public New Jersey university, given during COVID-19 pandemic in spring, 2021, to ascertain student perceptions of mechanisms and sense of belonging within the online classroom environment. Thirty-four (n = 34) Master's and Doctoral graduate students were enrolled in this course, which met for 3 hours weekly, for a 15 week semester. Qualitative data were collected from students, including 42 reflective posts per student (for a total of 1,428 reflections) and anecdotal observations at semester's end. Via qualitative reflexive thematic analysis, the following four themes emerged: (1) Recognizing the Moment, (2) Creating Empathic Connections, (3) Appreciating Availability/Flexibility, and (4) Clarity of Instruction. These themes are discussed, and implications for an actionable model for signature pedagogies embedded in trauma-informed care in graduate health science education are reviewed. [ FROM AUTHOR]

The Advocacy Efforts for School Library Staffing during the Pandemic

Amid the ongoing pandemic, school librarians across the country have been facing a different kind of battle, one that has been going on for years in some cases: the fight for every student to benefit from the instruction and carefully curated resources a certified school librarian can provide. Several states are working to introduce or retain legislation that requires a certified school librarian in every school building. States across the country have seen a decrease in certified school librarian staffing. In some districts, positions have been reduced dramatically or cut entirely despite research showing the benefits students, staff, and the entire school community receive from these specifically trained educators. State school library associations are working diligently with lawmakers, fellow state-level education organizations, and national-level partners to advocate on behalf of their students. This article are the stories from Arizona, Michigan, Nebraska, New Jersey, and Pennsylvania about their states' fights for the right of every student to receive the services provided by a certified school librarian.

Development of novel RT-PCR assay for detection of COVID-19 in the Post-Omicron Era

Background: We are facing a new era of the COVID-19 pandemic by omicron variant. This raises concern about the accuracy of conventional RTqPCR assays. There is a need for a new RTqPCR assay appropriate for the omicron variant with multiple mutations. Material(s) and Method(s): We herein have developed 2 types of new RTqPCR assays which detect G142D/del143-145, 452 and 478 of S, 69/70 of S or N, and internal control (IC) to make a new single tube, quadplex RTqPCR assay of COVID-19 ('GG COVID-19 Omicron and Delta kit'). Analytical performance was analyzed with Twist/BEI controls. Clinical performance analysis was done as a multi-center study in South Korea with specimens from New Jersey, collected between October 2021 and January 2022. Result(s): 400 left over nasopharyngeal swabs including 149 SARS-CoV-2 positive samples were collected and tested on January 2022 out of which 148 were due to omicron variant and 1 delta variant, respectively. S142-145 assay was superior to conventional RT-PCR(sensitivity 100% vs 00.0 to 00.0%, mean Ct value 25.0 vs 30.4 to 31.3). 330 samples including 125 SARS-CoV-2 positive samples from October 2021 and also tested, out of which 78 were due to delta and confirmed by sequencing. Conclusion(s): GG COVID-19 Omicron and Delta kit showed higher sensitivity than conventional RTqPCR (100% vs 95.4%) and 100% specificity in detecting SARSCoV-2 and could differentiate all of omicron variants. These results indicate that our GG COVID-19 Omicron and Delta kit may be more sensitive than conventional PCR assays in detecting Omicron and Delta SARS-CoV-2. Copyright © 2022

Molecular Biology of SARS-CoV-2 and its Evolution within the Princeton University Campus Community

Background. SARS-CoV-2, a novel and highly pathogenic coronavirus, has caused unprecedented global disruption following its introduction into the human population. Beginning in January 2021, a NJ university invited all students to campus and initiated an asymptomatic testing protocol using weekly to twice-weekly PCR-based detection of human saliva samples. RNA extracted from PCR-positive human saliva samples was sequenced for surveillance purposes. Methods. Positive samples were submitted for RNA-Seq analysis (ARTIC amplicon sequencing protocol, Illumina MiSeq) and analyzed using Nextclade and USHER (comparison data from GISAID). Using sequencing data, the evolution, transmission, and emergence of SARS-CoV-2 variants were monitored over time in the campus community. Using sequencing data from NY, PA, and NJ in combination with University data, we performed an IQ-TREE based phylogenetic analysis. Results. Analyzing sequencing data of 1,011 University positive samples we demonstrate that SARS-CoV-2 variants Delta (B.1.617.2) and Omicron (BA.1 and BA.2) were first to emerge following widespread vaccination and, quickly, became predominant. These trends witnessed on campus preceded those same variants emerging in New Jersey, providing evidence of local campus spread distinct from the state-wide pandemic. The analysis of 2,359 total sequences from NY, PA, and NJ in combination with University data, provided evidence of the SARS-CoV-2 transmission chain on campus evolving from out-of-state (January 2021) to local (January 2022) spread over one year of the virus circulating within the community at large. Upon performing a Ct value analysis of 2,822 Princeton University sequences, no significant differences were discovered between N gene Ct values when grouped by age or vaccination status. However, there were significant differences in Ct values between strains. The Emergence of SARS-CoV-2 Variants at Princeton University This plot represents the emergence of SARS-CoV-2 clades at Princeton University, organized by Nextstrain clade and displayed as a proportion out of one. Dates of sample collection range from January 25, 2021, to March 1, 2022. X-axis represents SARS-CoV-2 sample test date (grouped by month);Y-axis represents the count per day organized by Nextstrain clade. Conclusion. Sequencing of positive SARS-CoV-2 samples from population screening of a highly vaccinated University campus community allowed the detection of emergence of new variants that became predominant on campus irrespective of the circulation of variants in the surrounding area.

Impact of the COVID-19 Pandemic on CMS Organ Procurement Organization Performance Metrics

Purpose: CMS introduced new performance metrics for Organ Procurement Organizations (OPO). CDC death records define donation eligible deaths, the denominator of the donation and transplant rate metrics. The COVID-19 pandemic has had an unprecedented and geographically varied impact on United States death statistics. Thus, we examined the potential impact of COVID-19 on the calculation of the OPO performance metrics. Method(s): Eligible deaths include hospitalized decedents with "donation appropriate" diagnoses. We extracted death certificate data from the CDC WONDER system for baseline years (2015-2019) and the CDC COVID Data Tracker (after 2019). CDC aggregates data by state and broad disease groups including Circulatory Death (CD), death from Cerebrovascular Disease ICD-10 i60-i69 and Ischemic Heart Disease ICD-10 i20-i25. Deaths related to COVID (ICD-10 U07.1) were separately grouped. The proportion of CD during the pandemic was compared to baseline and correlated with COVID. Result(s): At baseline, CD accounted for 66.2% of OPO eligible deaths, increasing markedly in 2020 and 2021. (Figure A) The week of April 11, 2020, the national proportion of CD peaked at +23.8% over baseline, paralleling the dramatic increase in the proportion of deaths due to COVID (20%). Early in the pandemic, the proportion of CD and COVID deaths were strongly correlated (2020 r=.44). This attenuated over time (2021: r=.25). The CD and COVID death association evolved as the pandemic spread geographically. (Figure B) In 2020, the change in proportion of CD varied from New York (+20.6%) to Massachusetts (-6.5%). The COVID - CD correlation was highest in the Northeast and Florida, (New Jersey [.78], New York [.75] and Florida [.75]). By 2021, the change in proportion of CD was highest in Mississippi (+14.5%) and lowest in West Virginia (-28.6%), while the COVID - CD correlation diminished and spread west (Florida [.65], Tennessee [.54] and California [.53]. Conclusion(s): Accurate eligible death assessment has been difficult, leading to a shift in calculations based on ICD-10 coded death certificates instead of OPO reported deaths. CD constitutes 2/3 of recorded donation eligible deaths historically, which has been substantially, but variably, impacted by the COVID-19 pandemic. Thus, these metrics based on CDC data may be sensitive to unanticipated and uneven shocks such as disease outbreaks, leading to inaccurate estimates of donor potential. CMS metrics should be refined to better account for external shocks such as the COVID-19 pandemic. (Figure Presented).

Automated Puff Tonometry in Comprehensive Community Based Screening for Vision Threatening Diseases during SARS-CoV-2

Purpose : Over 50% of individuals with vision-threatening disease (VTD) (e.g., diabetic retinopathy, glaucoma, macular degeneration) are unaware of their condition, and once diagnosed, 80% will not follow up for clinical care, especially since the onset of SARS-CoV-2 in 2020. Remote teleophthalmology with real-time robotic teleconsultation was implemented to include automated puff-tonometry (APT) as pre-triage to identify patients who require more detailed clinical assessment and treatment. Methods : 224 subjects (58% male) of average age 55 years were screened over 8 events. Following COVID-19 protocols screenings took place in New Jersey churches and health fairs featuring a high prevalence of African American and Hispanic subjects. Masked and self-reported vaccinated subjects underwent medical history, blood pressure, visual acuity (with pinhole), automated puff-tonometry (APT) for intraocular pressures (IOP), automated refraction, non-mydriatic retinal imaging, optical coherence tomography (OCT), and wearable visual field device (WVFD) testing. Face masks were fitted with surgical tape on the nose bridge to limit instrument fogging. To minimize equipment contact, all subjects were screened in the standing position, including APT and retinal imaging (Fig.1). Chi-square and t-tests were performed to assess factors associated with glaucoma referral. Subjects without IOP readings were excluded;significance was set at p<0.05. Results : 10.29% of measured eyes had an IOP>18 and underwent additional testing including OCT-B of the optic nerve head, nerve fiber layer, and ganglion cell complex. 31.43% of eyes with IOP>18 underwent teleconsultation with a glaucoma specialist, vs. 8.85% of eyes with IOP≤18 ((p<0.001), Table 1). The difference in mean age in subjects with glaucoma referral vs. without (57.42 vs. 51.61 years) was significant (p=0.008). Conclusions : APT was useful in supporting on-site OCT-B imaging and WVFD referral (37.67%, 8.52% of total subjects) that yielded 17.94% referral to on-site teleconsultation through a real-time telerobot. Future investigation will include larger and more diverse community-based populations.

Digital Media Effect on Diabetic Eye Care During COVID-19 pandemic

Purpose : To gauge the impact of healthcare technology in the management of diabetic retinopathy during the COVID-19 pandemic. Methods : The study was conducted at EyeCare Consultants of New Jersey's in their two locations in NJ, Woodland Park and Edison. Eye care professionals (ECPs-two ophthalmologists, one optometrist) surveyed 400 diabetic patients during the first year of the pandemic (March 2020- February 2021). The patients all received previous instructions with CheckedUp, a patient education digital platform utilizing audiovisual and touchscreen to further educate patients, during in-office visits. The 400 diabetic patients were divided equally into two groups. To ensure the adherence of dietary and behavioral modifications related to diabetes mellitus, Group 1 received traditional phone calls while Group 2 received video calls and supplementary education with CheckedUp. Both groups had a follow-up in person in September 2021. Surveys elicited responses to gauge consistency of HbA1C management. Results : Adherence was defined as HbA1C values which remained within a target value lower than or equal to their baseline and/or <7.0% as well as compliance with medications, dietary restrictions, regular physical activity and follow-up visits. The results found a significant difference between educating the patient with a phone call versus a video call and CheckedUp. At the next follow-up visit in person: Group 1 had an adherence of 48% (96 patients) and had several patients with HbA1C values exceeding the targeted value. Group 2 had an adherence of 69% (138 patients) and were more compliant with a healthier lifestyle. They also stated that their telehealth appointment with CheckedUp helped reinforce the importance of maintaining a normal HbA1C value. Conclusions : This study illustrates the ability of digital medicine platforms to supplement virtual and in-person consultations to manage diabetic retinopathy, especially during the pandemic. Compliance is an important matter in the management and preventing progression of diabetic retinopathy. Digital tools like CheckedUp assist with optimizing patient care in these unprecedented times.

Clinical characteristics and outcomes of COVID-19 disease in patients with cancer

Background: The Coronavirus Disease 2019 (COVID-19) has been nominated as a pandemic by the World Health Organization short after has spreaded globally. Unfortunately, even after several effective vaccines approved by FDA, COVID-19 cases are still surging. Compared to the general population, patients with cancer are more susceptible to COVID-19 for many aspects. Therefore, better understanding of the clinical characteristics of cancer patients with COVID-19 is urgently needed to spare these vulnerable patients from severe disease course. Methods: This retrospective study was completed in Capital Health Regional Medical Center, New jersey, USA. Adult patients with COVID-19 diagnosed between March 2020 and May 2021 were included in this study. All selected COVID-19 patients were stratified as two groups: Patients with cancer and patients without cancer. Other variables were included as age at diagnosis, gender, race/ethnicity, insurance status, obesity, comorbidity score, treatment of COVID-19, oxygen requirement and vital status. The Charlson Comorbidity Index was used to calculate the comorbidity score. Results: A total of 562 COVID-19 patients were included in this study;67 (12%) patients diagnosed with cancer. Patients with cancer were more likely to be older (73 vs. 62 years, p < 0.001), overweight (BMI 25-29.9) (39% vs 28%, p = 0.02), and have higher comorbidity score > 3 (58% vs 15%, p < 0.001) than patients without cancer. Patients with cancer more frequently received steroid therapies (52% vs. 34%, p = 0.003), remdesivir (21% vs. 4%, p < 0.001), and convalescent plasma (21% vs. 10%, p = 0.009). The rate of high flow oxygen therapy was higher in patients with cancer than patients without cancer (30% vs. 16%, p = 0.02). The days of mechanic ventilation, hospital stay, ICU admission were similar between two groups. Patients without cancer had better survival rate compared to patients with cancer (77% vs. 64%, p = 0.02). Patients with cancer had increased D-dimer level (2.4 vs. 1.6 mg/L, p = 0.08) compared to patients without cancer but it was not significantly different. Other laboratory findings were also similar between two groups, including WBC, neutrophils, lymphocytes, lactate, lactate dehydrogenase, creatine kinase, d-dimer, C-reactive protein, procalcitonin, fibrinogen, BNP, troponin, sodium, AST, ALT, and ferritin. Multivariable logistic regression analysis showed that patients with cancer were associated with increased odds of higher than 3 comorbidity score (OR 7.09 [3.85-13.05], p < 0.001) and oxygen therapy with nasal cannula up to 6 liters (OR 3.7 [1.04-13.5], p = 0.04). Conclusions: This present analysis showed that patients had increased risk of mortality compared to counterpart. Our results emphasize that cancer patients as a group are at higher risk due to advanced age and preexisting conditions.